Hannibal scored four goals in the first half to put away Fulton.
Two first half goals set the pace for Hannibal's victory over Chillicothe.
Mexico scored early, but Hannibal scored three unanswered to win 3-1.
Moberly scored in the final seconds to beat Hannibal 2-1.
Hannibal's loss to Kirksville means the Pirates must win out in order to claim a share of the NCMC title.
Allowing a goal in the final game of the two-day Laker Shootout forced the Hannibal boys soccer team to settle for second place.
Caleb Young's goal in the 42nd minute lifted Hannibal soccer to a 1-0 victory.
The Hannibal boys soccer team won with 16 seconds remaining in first overtime thanks to a goal by Nathan DeStefane.
Karson Westhoff's goal with nine minutes remaining lifted Hannibal to a 2-1 victory.