Two Missouri men are being sought by the Pittsfield (Ill.) Police Department after they were located with hundreds of grams of synthetic cannabinoids.

Ryan T. Waters, age 42, and passenger was Michael O. Frye, age 60, both of Troy, Mo., were originally stopped on April 5 in Pittsfield. The officer conducted a traffic stop of the vehicle in the 1300 block of West Washington Street.

During the stop, 767 grams of synthetic cannabinoids in 96 separate packages were discovered in the vehicle. Waters' driver's license was revoked in the State of Missouri.

The investigation indicated the subjects purchased the substance in Springfield, Ill., and were en route to Troy, Mo. The substance was submitted to the Illinois State Police Crime Lab for analysis.

Recently, the Crime Lab presented a report indicating the substance was, in fact, an unlawful controlled substance.

On April 30, a warrant of arrest was issued for Waters and Frye with a $10,000 bond each. Both subjects are still at large. Chief Kenneth Yelliott reminds citizens that synthetic cannabinoids can cause health effects that can be unpredictable and harmful — even life threatening. Anyone with information on the whereabouts of Waters or Frye is encouraged to contact the Pittsfield Police Department.